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Penicillamina [DCIT] Brand names, Penicillamina [DCIT] Analogs

Penicillamina [DCIT] Brand Names Mixture

  • No information avaliable

Penicillamina [DCIT] Chemical_Formula

C5H11NO2S

Penicillamina [DCIT] RX_link

http://www.rxlist.com/cgi/generic3/penicillamine.htm

Penicillamina [DCIT] fda sheet

Penicillamina_[DCIT] FDA

Penicillamina [DCIT] msds (material safety sheet)

Penicillamina_[DCIT] MSDS

Penicillamina [DCIT] Synthesis Reference

No information avaliable

Penicillamina [DCIT] Molecular Weight

149.212 g/mol

Penicillamina [DCIT] Melting Point

198.5 oC

Penicillamina [DCIT] H2O Solubility

1.11E+005 mg/L

Penicillamina [DCIT] State

Solid

Penicillamina [DCIT] LogP

-2.09

Penicillamina [DCIT] Dosage Forms

Capsule; Tablet

Penicillamina [DCIT] Indication

For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis

Penicillamina [DCIT] Pharmacology

Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.

Penicillamina [DCIT] Absorption

rapidly but incompletely

Penicillamina [DCIT] side effects and Toxicity

No information avaliable

Penicillamina [DCIT] Patient Information

No information avaliable

Penicillamina [DCIT] Organisms Affected

Humans and other mammals